1.Chronic diseases
2. AIDS
3. Cancer
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Allergic inflammatory reactions are induced by Th2 cells overproduction
of IL-4, the B cell costimulatory cytokine. IL-4, in the presence
of antigen, activates specific B cells to produce Abs of the
IgE class which bind to IgE receptors carried by basophils
or mast cells. In the presence of Ag, these cells are triggered
to expel their granules and discharge histamine and other
mediators of tissue inflammation into the milieu. NEOVACS'
IL-4 kinoid targets this cytokine's overproduction by inducing
neutralizing Abs against this cytokine.
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