Patents and Pharmaceutical Products


Active anti-cytokine therapy : Kinoids (Patents WO 92/22577 ; WO 00/64937)

IFNa kinoid in AIDS and SLE
IL-4 kinoid in Allergy
VEGF kinoid in neoangiogenesis (cancer)
IL-10 kinoid in immunosuppression (cancer and viral diseases)
TNFa kinoid in Rhumatoid Arhtritis and Crohn's disease

Antiretroviral toxoids in AIDS and other retroviral diseases targeting stromal disorders (Patents WO 96/27389; WO 99/33872)

Tat toxoid in AIDS (Exclusive licence for AIDS to Aventis Pasteur)
Tax toxoid in Acute T cell Lymphoma (ATL)

Anti-immunosuppressive/anti-angiogenic toxoid (Patents WO 00/03732; WO 01/43771; FR 0205173 )

HPV-16 E7 Toxoid

Procedures to produce immunogenic heterocomplexes (Patents FR/ 0110751; FR/ 0211455)

TOXOID and KINOID to induce high titers of human neutralizing polyclonal Abs directed to soluble pathogenic stromal factors